Check Intently (one)pentobarbital will minimize the extent or result of fentanyl transdermal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Closely. Coadministration of fentanyl with CYP3A4 inducers may lead into a lessen in fentanyl plasma concentrations, lack of efficacy or, quite possibly, development of the wit… Read More